Xenodrum,
I'm sure it's been covered elsewhere, and to reach too far off topic, but, yes. St. Basil was constantly accused of heresy by many monks (especially he was accused of Macedonianism). St. Athanasius had the accusation of Sabellianism, but, it was more than just an Arian slander; Marcellus of Ancyra, his good friend, with whom St. Athanasius broke and re-established communion with 3 times, was indeed a crypto-Sabellian (indeed, Marcellus' pupil was the notorious Photinus). St. Hilary of Poiter's accepted the term 'Homoiousian' as long as he thought it was a compromise in words only, and that it's promoters accepted the co-eternal nature of the Son and Spirit with the Father. St. Paulinus of Antioch, the leader of the strident Eustathian True Orthodox party, consistently had not only the support and communion of Rome and Alexandria (being the only Orthodox patriarchate), but, attack St. Meletius as being heretical, schismatic, without grace, a fraud, and disreputable (they baptised people baptized by St. Meletius, and ordained those ordained by him). St. Meletius was only vindicated at the Second Council.
The spiritual genius and vision of St. Athanasius, guided by the Holy Ghost, was he saw in the word 'homousios' more than a term. Although he acknowledge that many of the bishops who refused communion with him (the majority of the 'conservative' eastern bishops in the new generation after Nicea I that rejected the council because of the term) did hold the same Faith, but, had been led wrongly to reject the clarifying phrase. This was done because, by using terms like 'homiousios' or 'homoian', that is, calling the Son of 'like essence' to the Father, or even 'like the Father' (the later phrase St. Athanasius had used in the "On the Incarnation of the Word", written before Nicea), he saw the lingering force of heresy and its sure hiding place. Arians could readily accept these terms, and some could those who had Orthodox intentions in many or some cases; but, this was the problem. It lacked clarity and hid heresy with professed Orthodoxy. The term 'homousios' however was the shibboleth that could once and for all distinguish Orthodoxy from heresy, after it was properly explained and defended (as St. Athanasius spent a career profitably doing).
IN Christ,
Fr. Enoch