It is interesting that that the saint says there will be no death in the time of Antichrist. Recently I was reading some speculation on a protestant end-times website suggesting the possibility that the mark of Antichrist will not only be a type of brand, and necessary for taking part in commerce, similar to a bar-code, but may be a very advanced piece of technology that allows the bearer to interface with Antichrists system on various levels.
The trans-humanist movement, that seeks by technological means to improve human beings in order to bring them to a blissful, deathless state outside of the grace of God, has been working for years and spending huge amounts of money and resources to develop drugs, implants etc. that can reverse the aging process, increase intelligence and enhance the healing and regenerative functions of the body. There is also research into augmentation of the senses, such as the Google glass device that overlays information onto whatever the user is looking at, and enhancement of the strength and endurance of the body through exoskeletons and cyborg type prosthesis to replace limbs or organs with higher powered or enhanced versions.
Consider also the proven ability of certain microwave and elf transmissions to project certain wavelengths into the population in order to pacify or agitate people, manipulating thoughts and passions to create a group-mind effect. Margaret Thatchers government used this technology in the 80's to pacify unruly parts of London and the CIA patented a technique for 'Synthetic Telepathy,' the actual insertion of thoughts in a targets mind, many decades ago.
It is possible that the Antichrist's mark will combine a receiver for these transmissions, perhaps a drip-feed of certain chemicals that induce a euphoric, blissful state (or it's opposite, if need be,) and perhaps some kind of miniaturized nano-tech robots that enter the bloodstream and induce some form of genetic or cellular changes that prevent aging or even death.
I can imagine certain of his servants may be provided with a higher level version of this mark, integrated with augmented body parts or senses, at the cost of a more powerful integration with his computerized networked mind, acting out his orders and implementing plans with total obedience, just like the demonic realm is organized.
This is pretty sci-fi, I know, but when we watch films or read books about future worlds, advanced systems such as the ones I am speaking of are usually presented alongside an environment that is equally advanced or different to our own. In popular science fiction the cities, buildings, clothes etc. are made to look like something from the future to match the level of technology that has been achieved. Most people don't realize just how far these developments, in genetics, remote mind-control, cybernetics, computer-human interface etc. have come, because in the real world, most things have stayed much the same and these technologies have been developed quietly and released to the population incrementally while people still live in houses built decades ago.
For the holy people who have foreseen the days of Antichrist it would be difficult to comprehend such technology and understand how it worked, even if they saw it in vision, and, from what I have read, there is no reason to assume that many of the things St John saw in his vision may not be super-advanced technology or weaponry that exists in the future and may even be fully developed and functional right now, but is kept out of sight, or relegated to the realm of science fiction, so that when the time comes for the Antichrist to be revealed, those powers he uses to dazzle the world and the benefits he offers those who serve him will seem to be an inevitable, irresistible, almost magical solution for every human ill to those who have not made some effort to prepare themselves to resist him.